Viseon Announces First Human Use of Hubble™ EXCITE

Viseon reports the first patient treated using Hubble EXCITE in a glioblastoma brain surgery by Dr. Ian Lee, Residency Program Director, Co-Director Hermelin Brain Tumor Center, Neurosurgeon at Henry Ford Health. The Hubble EXCITE device was used through a left parietal craniotomy for dissection and fluorescence guided imaging. Dr. Lee stated, “It was an honor to be the first to use Hubble EXCITE. The technology will be a valuable resource for hospital operating rooms. Incorporating multiple functions into one device simplifies OR setup and I am excited about the new features coming. The image quality was high resolution and clear, letting me operate and switch easily between white and blue light for tumor fluorescence.”

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Brain surgery by Dr. Lee using the Viseon Hubble EXCITE 4K image displayed for primary visualization and observation by the surgical team.

Hubble EXCITE is a first-of-its-kind device that integrates aspiration, dual-illumination, and 4K advanced digital visualization (4K-ADV) into a sterile, single use instrument. Hubble’s cutting-edge imaging system tracks the distal tip of the device for dynamic visualization, eliminating the need for scope-based repositioning. The dual-illumination feature gives the surgeon control to easily and instantly switch between white light and blue light for 5-ALA excitation. The resulting fluorescing image allows the surgeon to differentiate tissue, identify tumor margins, and selectively remove disease. The Hubble platform has been designed to seamlessly integrate with existing operating room equipment minimizing capital outlay.

"The first use of Hubble EXCITE realized our goal for improving surgeon tissue selectivity. Hubble EXCITE puts the imaging experience literally in the surgeon’s hand and allows them to switch between white light for standard surgical approach and with the push of a button, change to blue excitation light compatible with 5-ALA, a drug absorbed, specifically in a high-grade glioblastoma. The Hubble EXCITE with dual-illumination, optimized optics and image tuning provides a visual output for differentiating tumor tissue margins to assist surgeon decision making,” said Pete Davis, President & CEO of Viseon Inc. Adding, “The expansion of the Hubble therapeutic visualization platform should see continued use in open and minimally invasive brain surgery to address multiple neurosurgical diseases. The surgeon community has shown great interest in our technology, and we will continue to work with them to build clinical experience and expand market adoption.”

Viseon has rapidly developed the Hubble platform with the initial release this year of Hubble AV, a combined imaging-therapeutic system primarily used in hemorrhages for visualization during fluid and tissue aspiration. In March 2025, Viseon Inc. announced the first Hubble AV used in a patient that underwent a right frontal craniotomy for a tumor resection by Dr. Gabriel Zada, Professor of Neurological Surgery and Surgical Director of the USC Brain Tumor Center. In September 2025, Viseon announced the first Hubble AV use in a patient with an Intracerebral Hematoma from a minimally invasive neurosurgical approach by Dr. Jonathan Yun, Clinical Instructor of Neurosurgery, NYU Grossman School of Medicine, at Valley Hospital.

Viseon is developing a series of novel therapeutic imaging devices that add the imaging component to other minimally invasive and open surgical tools traditionally used in the brain for more accurate diagnosis and therapy. Viseon believes that this broad product platform, combining 4K imaging with routinely used instruments will create valuable therapeutic tools and smarter instruments, leading to superior clinical results and operating room efficiencies without capital intensive hospital resources.

The Hubble EXCITE System’s digital platform enables case recording, post-operative review, advanced training, patient education, and adaptation to emerging technologies such as mixed reality solutions, robotic-assisted surgery, AI surgical support, and remote proctoring.

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The first use of Hubble EXCITE realized our goal for improving surgeon tissue selectivity. Hubble EXCITE puts the imaging experience literally in the surgeon’s hand